A look at well-being, expectations and psychological adaptation in coeliac disease, from a biopsychosocial perspective
DOI:
https://doi.org/10.67799/prolepsis.2026.13.1.01Keywords:
celiac disease, quality of life, biopsycho-social perspective, emotional symptoms, psychological supportAbstract
Background: Coeliac disease (CD) has an impact that extends beyond the digestive system, affecting emotional, social and cognitive aspects that significantly influence quality of life. Its biological dimension is closely interlinked with the physical, social and psychological aspects, such that any change in one of these tends to have an effect on the others. Method: Through a systematic review, this paper provides an up-to-date synthesis of eleven recent studies. It analyses, from a biopsychosocial perspective, the main factors involved in the subjective perception of a loss of well-being. Results: Evidence suggests that anxiety arising from constant vigilance, the social burden associated with dietary management, fatigue and certain cognitive processes contribute to a state of persistent distress. This situation persists even when physical symptoms are successfully kept under control. Conclusion: The constant, multifactorial emotional burden calls for new approaches with a holistic and cross-cutting scope. It is necessary to provide psychological counselling and strategies for adapting to chronic conditions tailored to each individual. Utilising this synergy through psychology not only alleviates distress but also improves adherence to the gluten-free diet (GFD), thereby having a positive impact on overall well-being.
References
Alkhayyat, M., Qapaja, T., Aggarwal, M., Almomani, A., Abureesh, M., Al-otoom, O., Zmaili, M., Mansoor, E., & Abou Saleh, M. (2021). Epidemiology and risk of psychiatric disorders among patients with celiac disease: A population-based national study. Journal of Gastroenterology and Hepatology, 36(8), 2165-2170. https://doi.org/10.1111/jgh.15437
Dochat, C., Afari, N., Satherley, R.-M., Coburn, S., & McBeth, J. F. (2024). Celiac disease symptom profiles and their relationship to gluten-free diet adherence, mental health, and quality of life. BMC Gastroenterology, 24(1), Article 1. https://doi.org/10.1186/s12876-023-03101-x
Efe, A., & Tok, A. (2024). Obsessive–Compulsive Symptomatology and Disgust Propensity in Disordered Eating Behaviors of Adolescents with Celiac Disease. International Journal of Behavioral Medicine, 31(1), 85-96. https://doi.org/10.1007/s12529-023-10163-4
Elwenspoek, M., Banks, J., Desale, P. P., Watson, J., & Whiting, P. (2024). Exploring factors influencing quality of life variability among individuals with coeliac disease: An online survey. BMJ Open Gastroenterology, 11(1), e001395. https://doi.org/10.1136/bmjgast-2024-001395
Fisicaro, F., Lanza, G., D’Agate, C. C., Pennisi, M., Cantone, M., Pennisi, G., Hadjivassiliou, M., & Bella, R. (2022). Cerebral hemodynamic changes to transcranial Doppler sonography in celiac disease: A pilot study. Frontiers in Human Neuroscience, 16. https://doi.org/10.3389/fnhum.2022.931727
Günther, C., Rothhammer, V., Karow, M., Neurath, M. F., & Winner, B. (2021). The Gut-Brain Axis in Inflammatory Bowel Disease—Current and Future Perspectives. International Journal of Molecular Sciences, 22(16), Article 16. https://doi.org/10.3390/ijms22168870
Hayes, S. C. (2015). Terapia de Aceptación y Compromiso. Desclée De Brouwer.
Lee, A. R., Lebwohl, B., Lebovits, J., Wolf, R. L., Ciaccio, E. J., & Green, P. H. R. (2021). Factors Associated with Maladaptive Eating Behaviors, Social Anxiety, and Quality of Life in Adults with Celiac Disease. Nutrients, 13(12), 4494. https://doi.org/10.3390/nu13124494
Marsilio, I., Canova, C., D’Odorico, A., Ghisa, M., Zingone, L., Lorenzon, G., Savarino, E. V., & Zingone, F. (2020). Quality-of-Life Evaluation in Coeliac Patients on a Gluten-Free Diet. Nutrients, 12(10), 2981. https://doi.org/10.3390/nu12102981
Payette, C. C., Desjardins, C., Lalanne, E., Marquis, M., & Perreault, M. (2025). Exploring Challenges Faced by Adults Living With Celiac Disease: A Food Literacy Perspective. Journal of Human Nutrition and Dietetics, 38(2), e70057. https://doi.org/10.1111/jhn.70057
Skjellerudsveen, B. M., Omdal, R., Hetta, A. K., Kvaløy, J. T., Aabakken, L., Skoie, I. M., & Grimstad, T. (2022). Fatigue: A frequent and biologically based phenomenon in newly diagnosed celiac disease. Scientific Reports, 12(1), Article 1. https://doi.org/10.1038/s41598-022-11802-8
Stroebele-Benschop, N., Rau, C. J., Dieze, A., & Bschaden, A. (2025). Life Challenges and Quality of Life of People Living With Coeliac Disease: Time of Diagnosis Matters. Journal of Human Nutrition and Dietetics, 38(1). https://doi.org/10.1111/jhn.13413
Tricco, A. C., Lillie, E., Zarin, W., O’Brien, K. K., Colquhoun, H., Levac, D., Moher, D., Peters, M. D. J., Horsley, T., Weeks, L., Hempel, S., Akl, E. A., Chang, C., McGowan, J., Stewart, L., Hartling, L., Aldcroft, A., Wilson, M. G., Garritty, C., … Straus, S. E. (2018). PRISMA extension for scoping reviews (PRISMA-ScR): Checklist and explanation. Annals of Internal Medicine, 169(7), 467–473. https://doi.org/10.7326/M18-0850
Wheeler, M., David, A. L., Kennedy, J., & Knight, M. (2022). “I sort of never felt like I should be worried about it or that I could be worried about it’” an interpretative phenomenological analysis of perceived barriers to disclosure by young people with coeliac disease. British Journal of Health Psychology, 27(4), 1296-1313. https://doi.org/10.1111/bjhp.12599
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.